Briefing: What keeps centrioles together: NuSAP's newly mapped role in centrosome integrity

Biologists at the National University of Singapore have identified the protein NuSAP as essential for the structural integrity of centrioles, which are crucial components of the cell's centrosome.

This discovery reveals a mechanism by which NuSAP contributes to the stability of centrioles, potentially influencing cellular processes linked to developmental disorders.

The findings suggest that disruptions in NuSAP function may be associated with conditions such as microcephaly and mosaicism, warranting further investigation into its role in cell biology and disease.